Drug name: Injectable acetaminophen (ACETAMINOPHEN 150MG / ML 6.7ML VIAL)


What are the uses and uses of this drug?

Acetaminophen is generally used as an analgesic and antipyretic. As an analgesic, it is usually used for mild to moderate pain, especially after surgery. It is also used as an antipyretic in situations where fever reduction is desirable.


Is this medicine used in a hospital or a pharmacy?

The main use of this drug is in the hospital and mainly in patients who are unable to use the oral form of acetaminophen for them. But it can also be used in clinics and offices of doctors who have injections if needed.


How to prepare this medicine is OTC or with a doctor’s prescription?

This medicine is prepared only with a doctor’s order and prescription and is used for the patient.


What are the other important products that can replace this product in any therapeutic application? What are the strengths and weaknesses of this product compared to the mentioned products?

Acetaminophen is used as a first-line analgesic and antipyretic in many patients, especially in mild to moderate pain and its injectable form to relatively severe pain. In severe pain (such as pain experienced by cancer patients), the analgesic effects of acetaminophen may not be enough to control the patient’s pain, but acetaminophen can reduce the dose of opioid needed to control the patient’s pain. Give. In general, side effects with acetaminophen are rare and there is concern about the misuse of overdoses. Also, alcoholics are more likely to be poisoned by acetaminophen, which is less common in Iran. Acetaminophen should be used with caution in people with liver problems and requires dose adjustment. In general, if acetaminophen is prescribed at the right dose and appropriate to the patient’s condition, side effects with acetaminophen are very rare.
Another advantage of acetaminophen is that it is compatible with breastfeeding at the recommended doses. Acetaminophen is also safer than other painkillers during pregnancy. However, information on acetaminophen use in pregnancy is derived from oral acetaminophen and cannot be easily extended to intravenous acetaminophen. Other major drugs used as analgesics and antipyretics include: 1- NSAIDs ( Ibuprofen: NSAIDs have anti-inflammatory and anti-inflammatory effects in addition to their antipyretic and analgesic effects. Therefore, if the patient’s pain is inflammatory in nature, NSAIDs are potentially more effective. However, due to the side effects of NSAIDs (especially gastrointestinal, renal and cardiovascular complications), the use of acetaminophen is a priority. NSAIDs Ketorolac, ibuprofen, diclofenac and piroxicam are available in Iran by injection.

2. Opioid drugs (morphine family drugs): Used for moderate to severe pain, but even if these drugs are used, at least according to the results of some studies, acetaminophen can be used simultaneously. ¬ Can reduce the required dose of opioid drug to control the patient’s pain. The distribution and availability of opioid drugs is, of course, controlled and by the method of purification.
[1] Non-Steroidal Anti Inflammatory Drugs


What suggestions do you have for strengthening the position of this product in the market and in comparison with other products and competitors?

Acetaminophen is a unique drug (in terms of safety) in the group of analgesics and antipyretics, and there is no other drug that has acceptable analgesic effects and is as safe as acetaminophen. NSAIDs are generally only available for short periods of time due to the potential for side effects. Therefore, one way to increase the competitiveness of this product is to promote it scientifically and in fact introduce it as a low analgesic and antipyretic drug. Complications compared to other available drugs. A drug that, in fact, should not be used if other patients’ pain can be controlled. In addition, due to the fact that there are other suppliers for this product, the quality of the product as well as its packaging form is important. Given the significant consumption of injectable acetaminophen in different parts of the hospital, it is likely Packing in packs of 10 is more appropriate.
In pediatric wards, a small amount of a vial is sometimes used depending on the patient’s weight, and the product is discarded frequently. For example, if the remaining amount could be used as the next dose in the form of a vial, it could be an advantage, but according to the study, external vials made as a solution for infusion (1000mg / 100mL) And they can not be stored after opening and the remaining amount should be discarded.


Which group of doctors and specialists prescribe this drug? Please indicate the amount of prescription in order.

First: Surgeons in various specialized fields, especially general and orthopedic surgeons. ) Even general practitioners and emergency physicians: in the next stage of use in doctors’ offices and clinics that can perform injections.
What other drug forms does this product have? What is the consumption of other forms of medicine compared to this product?
Acetaminophen is available in solid and liquid oral forms (including in combination with other drugs, such as anti-cold products, etc.) as well as in suppository form. Oral forms of acetaminophen, of course, make sense to be more widely consumed. The use of suppositories in our culture is not very desirable for patients.


Which form of this drug is more medically advantageous?

The use of oral form is as much a priority as possible according to the general approach in pharmacotherapy. In case of lack of access to oral method for drug administration, of course, it is necessary to use the injectable form. The injection form for more severe pain may be faster and more effective.
Due to the applications of acetaminophen and a wide range of patients in which the drug can be used as an analgesic and antipyretic, the injectable product of acetaminophen is a very valuable product in the treatment environment.

 


Other scientific product information for preparing scientific and promotional brochures

Important points were mentioned in the previous paragraphs. Due to the sensitivity of the prescribed dose of acetaminophen to the patient, it is appropriate that the prepared brochures provide information on how to dose the drug in the form of tables understandable to the doctor and the patient according to age, weight and other clinical conditions. In a way that facilitates the prescription and use of the appropriate dose for the doctor, nurse and possibly the pharmacist.


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