Introduction of Mesna medicine
Injections of oromitexan or mesna are used to treat the harmful effects of some cancer drugs on the bladder.
Uses of Mesna
Mesna is used to prevent hemorrhagic cystitis in patients treated with lymphosphamide and cyclophosphamide.
Mechanism of mesna effect
Mesna binds to the metabolites of cyclophosphamide and ifosfamide in the kidney and reduces their toxic effects.
Pharmacokinetics of mesna
The half-life of the drug is 0.36 hours and its excretion is renal.
Allergic reactions, diarrhea, nausea and vomiting are common complications of old age.