Mesna

Introduction of Mesna medicine

Injections of oromitexan or mesna are used to treat the harmful effects of some cancer drugs on the bladder.

Uses of Mesna

Mesna is used to prevent hemorrhagic cystitis in patients treated with lymphosphamide and cyclophosphamide.

Mechanism of mesna effect

Mesna binds to the metabolites of cyclophosphamide and ifosfamide in the kidney and reduces their toxic effects.

Pharmacokinetics of mesna

The half-life of the drug is 0.36 hours and its excretion is renal.

Warnings Mesna